舞蹈症相关蛋白1抗体
规格：1mg/1ml
英文名： HAP1
别名： Huntingtin Associated Protein 1; HAP 1; HAP 2; HAP-1; Hap1; HAP1_HUMAN; HAP2; HAPP; hHAP1; hHLP1; HIP 5; HIP5; HLP; HLP1; Huntingtin-associated protein 1; huntingtin-associated protein 2; Neuroan 1; N
分子量： 75kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HAP1
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆
舞蹈症相关蛋白1抗体产品介绍：background: Huntingtin-associated protein 1 binds to Huntingtin. Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of Huntingtin that leads to Huntington’s disease (HD). The ability of HAP1 to bind to Huntingtin is enhanced by an expanded polyglutamine repeat region. HAP1 shows neuronal localization and moves with Huntingtin in nerve fibers. HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem. HAP1 in rat has been shown to associate with a number of intracellular organelles. Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons. Function: Associates specifically with huntingtin. 舞蹈症相关蛋白1抗体This binding is enhanced by an expanded polyglutamine repeat. Tissue Specificity: Predominantly expressed in brain. Selectively expressed in neurons. Similarity: Contains 1 HAP1 N-terminal domain. Gene ID: 9001 Database links: Entrez Gene: 9001 Human Entrez Gene: 15114 Mouse Entrez Gene: 29430 Rat Omim: 600947 Human SwissProt: P54257 Human SwissProt: O35668 Mouse SwissProt: P54256 Rat 舞蹈症相关蛋白1抗体Unigene: 158300 Human Unigene: 281700 Mouse Unigene: 37430 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
舞蹈症相关蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid