GTP发育调控结合蛋白1抗体
规格：1mg/1ml
英文名： DRG1
别名： Developmentally regulated GTP binding protein 1; Developmentally-regulated GTP-binding protein 1; DRG 1; DRG-1; DRG1; DRG1_HUMAN; NEDD 3; NEDD-3; NEDD3; Neural precursor cell expressed developmentally
分子量： 41kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DRG1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：细胞浆
GTP发育调控结合蛋白1抗体产品介绍：background: May play a role in cell proliferation, differentiation and death.High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. Function: Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest. Subunit: Interacts (via its C-terminal) with TAL1. Interacts with ZC3H15; the interaction forms a polysomal DRG1-DFRP1/ZC3H15 complex which provides protein stability to DRG1 possibly by blocking poly-ubiquitination. Interacts with STK16; the interaction phosphorylates STK16 Subcellular Location: GTP发育调控结合蛋白1抗体Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes. Tissue Specificity: High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. Post-translational modifications: Sumoylated by UBE2I in response to MEKK1-mediated stimuli. Similarity: Belongs to the GTP1/OBG family. Contains 1 G (guanine nucleotide-binding) domain. Gene ID: 4733 Database links: Entrez Gene: 4733 Human Entrez Gene: 13494 Mouse Entrez Gene: 305470 Rat Omim: 603952 Human SwissProt: Q9Y295 Human SwissProt: P32233 Mouse SwissProt: Q5I0F0 Rat Unigene: 115242 Human Unigene: GTP发育调控结合蛋白1抗体3250 Mouse Unigene: 102143 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GTP发育调控结合蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 发育生物学 信号转导 细胞周期蛋白 转录调节因子 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid