转录因子E2F7抗体
规格：1mg/1ml
英文名： E2F7
别名： E2F 7; E2F transcription factor 7; E2F-7; E2f7; E2F7_HUMAN; FLJ12981; Transcription factor E2F7.
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human E2F7
交叉反应：Human,
细胞定位：
转录因子E2F7抗体产品介绍：Function: Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Subunit: Homodimer and heterodimer: mainly forms homodimers and, to a lesser extent, heterodimers 转录因子E2F7抗体with E2F8. Dimerization is important for DNA-binding. Interacts with HIF1A. Subcellular Location: Nucleus. Similarity: Belongs to the E2F/DP family Gene ID: 144455 Database links: Entrez Gene: 144455 Human Entrez Gene: 52679 Mouse Entrez Gene: 314818 Rat Omim: 612046 Human SwissProt: E1BE02 Cow SwissProt: Q96AV8 Human SwissProt: Q6S7F2 Mouse SwissProt: D4A4D7 Rat Unigene: 416375 Human Unigene转录因子E2F7抗体: 11747 Mouse Unigene: 211183 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子E2F7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 **学 染色质和核信号 信号转导 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid