转录因子E2F8抗体
规格：1mg/1ml
英文名： E2F8
别名： E2F 8; E2F family member 82; E2F transcription factor 8; E2F-8; E2f8; E2F8_HUMAN; FLJ23311; Transcription factor E2F8.
分子量： 94kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human E2F8
交叉反应：Human,
细胞定位：
转录因子E2F8抗体产品介绍：Function: Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Subunit: Forms heterodimers with E2F7 and, to a lesser 转录因子E2F8抗体extent, homodimers. Dimerization is important for DNA binding. Subcellular Location: Nucleus. Similarity: Belongs to the E2F/DP family Gene ID: 79733 Database links: Entrez Gene: 79733 Human Entrez Gene: 108961 Mouse Entrez Gene: 308607 Rat Omim: 转录因子E2F8抗体612047 Human SwissProt: A0AVK6 Human SwissProt: Q58FA4 Mouse Unigene: 523526 Human Unigene: 240566 Mouse Unigene: 395068 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子E2F8抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 **学 染色质和核信号 信号转导 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid