磷酸变位酶1抗体
规格：1mg/1ml
英文名： PGAM1
别名： BPG dependent PGAM 1; BPG dependent PGAM1; BPG-dependent PGAM 1; OTTHUMP00000059414; PGAM 1; PGAM A; PGAM B; PGAM-B; PGAM1; PGAM1_HUMAN; PGAMA; PGAMB; Phosphoglycerate mutase 1; Phosphoglycerate mutas
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human PGAM1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：
磷酸变位酶1抗体产品介绍：Function: Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. Subunit: Homodimer. Tissue Specificity: In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles磷酸变位酶1抗体 and type-B in other tissues. Post-translational modifications: Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. Similarity: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. Gene ID: 5223 Database links: UniProtKB/Swiss-Prot: P18669.2 Entrez 磷酸变位酶1抗体Gene: 5223 Human Entrez Gene: 18648 Mouse Entrez Gene: 24642 Rat Omim: 172250 Human SwissProt: P18669 Human SwissProt: Q9DBJ1 Mouse SwissProt: P25113 Rat Unigene: 592599 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸变位酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 免疫学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid