羧酸酯酶2抗体
规格：1mg/1ml
英文名： CES2
别名： Carboxylesterase 2 (intestine, liver); Carboxylesterase 2; CE-2; CES2; CES2A1; Cocaine esterase; EC 3.1.1.1; EST2_HUMAN; hCE-2; ICE; Iintestinal carboxylesterase liver carboxylesterase 2; Intestinal c
分子量： 59kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CES2
交叉反应：Human,
细胞定位：细胞浆
羧酸酯酶2抗体产品介绍：background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010] Function: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine. Subcellular Location: Endoplasmic reticulum lumen. Tissue Specificity: Preferentially expressed in intestine with moderate expression in liver. 羧酸酯酶2抗体Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum. Post-translational modifications: Glycosylated. Similarity: Belongs to the type-B carboxylesterase/lipase family. Gene ID: 8824 Database links: Entrez Gene: 8824 羧酸酯酶2抗体Human Omim: 605278 Human SwissProt: O00748 Human Unigene: 282975 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 羧酸酯酶主要位于肝、其他组织及细胞胞液、线粒体和内质网。 是一种多聚蛋白，主要催化酯、硫酸酯和酰胺的水解。
羧酸酯酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid