PRPF4蛋白抗体
规格:1mg/1ml
英文名: PRPF4
别名: HPRP4; HPRP4P; PRP4; PRP4 pre mRNA processing factor 4 homolog (yeast); PRP4/STK/WD splicing factor; Prp4p; U4/U6 small nuclear ribonucleoprotein Prp4; WD splicing factor Prp4; PRP4_HUMAN.
分子量: 58kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PRPF4
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞核
PRPF4蛋白抗体产品介绍:background: Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008] Function: Involved in pre-mRNA splicing. Subunit: Interacts directly with PRPF18, PPIH and PRPF3. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. PRPF4蛋白抗体This complex interacts with the U4/U5/U6 tri-snRNP complex. Subcellular Location: Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs. Similarity: Contains 7 WD repeats. Gene ID: 8899 Database links: Entrez Gene: 8899 Human Entrez Gene: 19134 Mouse Entrez Gene: 291078 Rat Omim: 602338 Human SwissProt: Q08DZ2 Cow SwissProt: Q13523 Human SwissProt: Q61136 Mouse SwissProt: Q5RKH1 Rat Unigene:PRPF4蛋白抗体 159014 Human Unigene: 10027 Mouse Unigene: 482253 Mouse Unigene: 32654 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PRPF4蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞周期蛋白 细胞分化 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid