转录因子Tbx5抗体
规格：1mg/1ml
英文名： TBX-5
别名： Holt Oram syndrome; HOS; T box 5; T box protein 5; T box transcription factor TBX 5; T box transcription factor TBX5; T-box protein 5; T-box transcription factor TBX5; TBX 5; TBX5; TBX5_HUMAN; Transcr
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TBX-5
交叉反应：Human, Mouse, Rat, Cow, Horse, Sheep,
细胞定位：细胞核
转录因子Tbx5抗体产品介绍：background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Function: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Subcellular Location: Nucleus. DISEASE: Defects in TBX5 are the cause of Holt-Oram syndrome (HOS) [MIM:142900]. 转录因子Tbx5抗体HOS is a developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects. Similarity: Contains 1 T-box DNA-binding domain. Gene ID: 6910 Database links: Entrez Gene: 373988 Chicken Entrez Gene: 6910 Human Entrez Gene: 21388 Mouse Entrez Gene: 304514 Rat Omim: 601620 Human SwissProt: O73719 Chicken SwissProt: Q96TB0 Human SwissProt: Q99593 转录因子Tbx5抗体Human SwissProt: P70326 Mouse SwissProt: Q5CZX7 Mouse SwissProt: Q5I2P1 Rat Unigene: 381715 Human Unigene: 103636 Mouse Unigene: 6327 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子Tbx5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid