蛋白质精氨酸亚型1抗体
规格：1mg/1ml
英文名： PADI1 / PAD1
别名： HPAD10; Padi1; PADI1_HUMAN; PDI; PDI1; Peptidylarginine deiminase I; protein arginine deiminase type I; Protein-arginine deiminase type I; Protein-arginine deiminase type-1.
分子量： 75kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PADI1 /
交叉反应：Human, Mouse, Rat, Sheep,
细胞定位：细胞浆
蛋白质精氨酸亚型1抗体产品介绍：background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence蛋白质精氨酸亚型1抗体 the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] Function: Catalyzes the deimination of arginine residues of proteins. Subcellular Location: Cytoplasm. Tissue Specificity: Epidermis, prostate, testis, placenta, spleen and thymus. Similarity: Belongs to the protein arginine 蛋白质精氨酸亚型1抗体deiminase family. Gene ID: 29943 Database links: Entrez Gene: 29943 Human Omim: 607934 Human SwissProt: Q9ULC6 Human Unigene: 412941 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产蛋白质精氨酸亚型1抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid