环磷酸腺苷调节磷酸蛋白PP16B抗体
规格：1mg/1ml
英文名： PPP1R1C
别名： ANKRD4; Ankyrin repeat domain containing protein 4; ankyrin repeat domain protein 4; Ankyrin repeat domain-containing protein 4; CAAX box protein TIMAP; hTIMAP; KIAA0823; PP16B_HUMAN; PPP1R16B; Protei
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PPP1R1C
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆
环磷酸腺苷调节磷酸蛋白PP16B抗体产品介绍：background: This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] Function: Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. Subcellular Location: Cytoplasm. Tissue Specificity: 环磷酸腺苷调节磷酸蛋白PP16B抗体Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level). Post-translational modifications: Phosphorylation at Ser-56 favors interaction with CALM1. Isoform 1 is methylated by CARM1 in immature thymocytes.环磷酸腺苷调节磷酸蛋白PP16B抗体 Similarity: Contains 1 R3H domain. Database links: Entrez Gene: 10777 Human Entrez Gene: 74100 Mouse Entrez Gene: 363153 Rat Omim: 605488 Human SwissProt: Q9UBL0 Human SwissProt: Q9DCB4 Mouse Unigene: 475902 Human Unigene: 713605 Human Unigene: 297444 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环磷酸腺苷调节磷酸蛋白PP16B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid