蛋白磷酸酶2调节亚基5A抗体
规格：1mg/1ml
英文名： PPP2R5A
别名： 2A5A_HUMAN; B56A; MGC131915; PP2A B subunit B' alpha isoform; PP2A B subunit B56 alpha isoform; PP2A B subunit isoform B''-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; P
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PPP2R5A
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
蛋白磷酸酶2调节亚基5A抗体产品介绍：background: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Subcellular Location: Cytoplasm. Nucleus. Chromosome > 蛋白磷酸酶2调节亚基5A抗体centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase. Tissue Specificity: Widely expressed with the highest expression in heart and skeletal muscle. Post-translational modifications: Phosphorylated on serine residues. Similarity: Belongs to the phosphatase 2A regulatory subunit B56 family. Gene 蛋白磷酸酶2调节亚基5A抗体ID: 5525 Database links: Entrez Gene: 5525 Human Entrez Gene: 226849 Mouse Entrez Gene: 312754 Rat Omim: 601643 Human SwissProt: Q15172 Human SwissProt: Q6PD03 Mouse Unigene: 497684 Human Unigene: 205569 Mouse Unigene: 104461 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白磷酸酶2调节亚基5A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid