催乳素调节元件结合蛋白PREB抗体
规格：1mg/1ml
英文名： PREB
别名： Mammalian guanine nucleotide exchange factor mSec12; Preb; PREB_HUMAN; Prolactin regulatory binding element protein; Prolactin regulatory element binding; Prolactin regulatory element binding protein;
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PREB
交叉反应：Human, Mouse, Rat, Rabbit,
催乳素调节元件结合蛋白PREB抗体细胞定位：细胞核
产品介绍：background: This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008] Function: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER. Subcellular Location: Nucleus. Endoplasmic reticulum membrane. 催乳素调节元件结合蛋白PREB抗体Tissue Specificity: Ubiquitous. Similarity:催乳素调节元件结合蛋白PREB抗体 Contains 3 WD repeats. Database links: Entrez Gene: 10113 Human Entrez Gene: 50907 Mouse Entrez Gene: 58842 Rat Omim: 606395 Human SwissProt: Q9HCU5 Human SwissProt: Q9WUQ2 Mouse SwissProt: Q9WTV0 Rat Unigene: 279784 Human Unigene: 272414 Mouse Unigene: 41899 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
催乳素调节元件结合蛋白PREB抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 生长因子和** 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid