β淀粉样蛋白结合蛋白抗体
规格：1mg/1ml
英文名： TM2D1
别名： BBP; Beta amyloid binding protein; hBBP; TM2 domain containing 1; TM2 domain containing protein 1; TM2D1.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TM2D1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
β淀粉样蛋白结合蛋白抗体产品介绍：background: The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq, Dec 2008] β淀粉样蛋白结合蛋白抗体Function: May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42. Subunit: Interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP. Subcellular Location: Membrane; Multi-pass membrane protein. β淀粉样蛋白结合蛋白抗体Tissue Specificity: Widely expressed. Post-translational modifications: N-glycosylated. Similarity: Belongs to the TM2 family. Gene ID: 83941 Database links: Entrez Gene: 83941 Human Entrez Gene: 94043 Mouse Entrez Gene: 362545 Rat Omim: 610080 Human SwissProt: Q9BX74 Human SwissProt: Q99MB3 Mouse Unigene: 656790 Human Unigene: 331719 Mouse Unigene: 198278 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β淀粉样蛋白结合蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞凋亡 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid