PATL1蛋白抗体
规格:1mg/1ml
英文名: PATL1
别名: hPat1b; OK/KNS-cl.5; PAT1-like protein 1; Pat1b; PATL1; PATL1_HUMAN; protein associated with topoisomerase II homolog 1; Protein PAT1 homolog 1; Protein PAT1 homolog b.
分子量: 87kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PATL1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位:细胞核 细胞浆
PATL1蛋白抗体产品介绍:background: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV). Subunit: Interacts (via region A) with DDX6/RCK. Interacts (via region H and region C) with LSM1 and LSM4. Interacts (via region N) with DCP1A, PATL1蛋白抗体DCP2, EDC3, EDC4 and XRN1. Interacts with the CCR4-NOT complex. Interacts with the Lsm-containing SMN-Sm protein complex. Subcellular Location: Cytoplasm > P-body. Tissue Specificity: Ubiquitous. Similarity: Belongs to the PAT1 family. Gene ID: 219988 DatabasePATL1蛋白抗体 links: Entrez Gene: 219988 Human Entrez Gene: 225929 Mouse SwissProt: Q86TB9 Human SwissProt: Q3TC46 Mouse Unigene: 591960 Human Unigene: 42711 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PATL1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转运蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid