多腺苷二磷酸多聚酶PARP9抗体
规格：1mg/1ml
英文名： PARP9
别名： ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; AW214463; B aggressive lymphoma protein; Bagl; BAL; BAL1; BC003281; DKFZp666B0810; DKFZp686M15238; EC 2.4.2.30; FLJ26637; FLJ35310; FLJ41418; FLJ
分子量： 97kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PARP9
交叉反应：Human, Mouse,
细胞定位：细胞核 细胞浆
多腺苷二磷酸多聚酶PARP9抗体产品介绍：Function: Involved in inducing the expression of IFN-gamma-responsive genes. Subcellular Location: Cytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L. Tissue Specificity: Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells. DISEASE: Note=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to 多腺苷二磷酸多聚酶PARP9抗体cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors. Similarity: Contains 2 Macro domains. Contains 1 PARP catalytic domain. Gene ID: 83666 Database links: Entrez Gene: 83666 Human Entrez Gene: 80285 Mouse SwissProt: Q8IXQ6 Human SwissProt:多腺苷二磷酸多聚酶PARP9抗体 Q8CAS9 Mouse Unigene: 518200 Human Unigene: 49074 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多腺苷二磷酸多聚酶PARP9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 b-**细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid