锌指蛋白ZNF746抗体
规格：1mg/1ml
英文名： PARIS/ZNF746
别名： PARIS; Parkin-interacting substrate; Zinc finger protein 746; ZN746_HUMAN; ZNF746.
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PARIS/ZN
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
锌指蛋白ZNF746抗体产品介绍：Function: Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. Subcellular Location: Cytoplasm. Nucleus. Mainly localizes to the cytoplasm; probably translocates to the nucleus to repress selected genes. Post-translational modifications: Ubiquitinated by PARK2. 'Lys-48'-linked polyubiquitination by PARK2 leads to degradation by the proteasome and may play 锌指蛋白ZNF746抗体a key role in regulation of neuron death. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 4 C2H2-type zinc fingers. Contains 1 KRAB domain. Gene ID: 155061 Database links: Entrez Gene: 155061 Human Entrez Gene: 69228 锌指蛋白ZNF746抗体Mouse Entrez Gene: 312303 Rat Omim: 613914 Human SwissProt: Q6NUN9 Human SwissProt: Q3U133 Mouse Unigene: 24643 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产锌指蛋白ZNF746抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 锌指蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid