RHOD蛋白抗体
规格:1mg/1ml
英文名: RHOD
别名: ARHD; Ras homolog D; Ras homolog gene family member A; Ras homolog gene family member D; Rho; RHO D; Rho related GTP binding protein RhoD; Rho related protein HP1; Rho-related GTP-binding protein RhoD
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RHOD
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
RHOD蛋白抗体产品介绍:background: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Function: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. Subunit: Interacts (in GTP-bound form) with DIAPH2 isoform 3, DAPK3, FILIP1 and WHAMM. RHOD蛋白抗体Interacts with PAK7/PAK5. Interacts (independent of GTP-loaded status) with ANKFY1. Subcellular Location: Cell membrane. Tissue Specificity: Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues. Similarity: RHOD蛋白抗体Belongs to the small GTPase superfamily. Rho family. Gene ID: 29984 Database links: Entrez Gene: 29984 Human Entrez Gene: 11854 Mouse Entrez Gene: 293660 Rat Omim: 605781 Human SwissProt: O00212 Human SwissProt: P97348 Mouse Unigene: 15114 Human Unigene: 27701 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RHOD蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid