G蛋白信号转导调节因子13抗体
规格：1mg/1ml
英文名： RGS13
别名： AL713991.1; HGNC:9995; MGC17173; OTTMUSP00000022853; OTTMUSP00000022854; Regulator of G protein signalling 13; RGD1562103; RGS 13; RP11 92K2.1.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RGS13
交叉反应：Human, Mouse, Rat, Dog,
细胞定位：
G蛋白信号转导调节因子13抗体产品介绍：background: The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants G蛋白信号转导调节因子13抗体encoding the same isoform exist. [provided by RefSeq, Jul 2008] Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha (By similarity). Similarity: Contains 1 RGS domain. Gene ID: 6003 Database links: Entrez Gene: 6003 Human Entrez Gene: 246709 MouseG蛋白信号转导调节因子13抗体Entrez Gene: 498246 Rat Omim: 607190 Human SwissProt: O14921 Human SwissProt: Q8K443 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白信号转导调节因子13抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid