单核细胞趋化蛋白2抗体
规格：1mg/1ml
英文名： MCP-2
别名： MCP2; CCL 8; CCL8; CCL8; CCL8_HUMAN; C-C motif chemokine 8; Chemokine CC Motif Ligand 8; Chemokine CC Motif Ligand 8; HC14; HC14; MCP-2; MCP-2(6-76); Monocyte chemoattractant protein 2; Monocyte Chemo
分子量： 8/9kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MCP-2
交叉反应：Human, Rat,
细胞定位：分泌型蛋白
单核细胞趋化蛋白2抗体产品介绍：background: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Jul 2008]. Function: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the 单核细胞趋化蛋白2抗体chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. Subunit: Monomer or homodimer; in equilibrium. Subcellular Location: Secreted. Tissue Specificity: Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, 单核细胞趋化蛋白2抗体spleen and prostate. Post-translational modifications: N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. Similarity: Belongs to the intercrine beta (chemokine CC) family. Gene ID: 6355 Database links: Entrez Gene: 6355 Human Omim: 602283 Human SwissProt: P80075 Human Unigene: 271387 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
单核细胞趋化蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid