转录延伸因子结合蛋白1抗体
规格:1mg/1ml
英文名: REXO1
别名: EloA BP1; ELOABP1; Elongin A binding protein 1; KIAA1138; REX1, RNA exonuclease 1 homolog (S. cerevisiae); RNA exonuclease 1 homolog; TCEB3BP1; Transcription elongation factor B polypeptide 3 binding
分子量: 131kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human REXO1
交叉反应:Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位:细胞核
转录延伸因子结合蛋白1抗体产品介绍:background: REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation 转录延伸因子结合蛋白1抗体in vivo. Function: Seems to have no detectable effect on transcription elongation in vitro. Subunit: Interacts with TCEA2 and TCEB3. Subcellular Location: Nuclear Similarity: Belongs to the REXO1/REXO3 family. Contains 1 exonuclease domain. Gene ID: 转录延伸因子结合蛋白1抗体57455 Database links: Entrez Gene: 57455 Human Omim: 609614 Human SwissProt: Q8N1G1 Human Unigene: 192477 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录延伸因子结合蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid