溶质载体家族蛋白39成员A4抗体
规格：1mg/1ml
英文名： SLC39A4
别名： 1600025H15Rik; Acrodermatitis enteropathica zinc deficiency type; Activated in W/Wv mouse stomach 2; AEZ; AU041686; AWMS2; FLJ20327; MGC156705; MGC74741; S39A4_HUMAN; Slc39a4; Solute carrier family 39
分子量： 66kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC39A4
交叉反应：Human, Rat,
细胞定位：细胞膜
溶质载体家族蛋白39成员A4抗体产品介绍：background: This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] Function: Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability. Subcellular Location: Cell membrane. Recycling endosome membrane. Colocalized with TFRC in the recycling endosomes. Cycles between 溶质载体家族蛋白39成员A4抗体endosomal compartments and the plasma membrane in response to zinc availability. Tissue Specificity: Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum. DISEASE: Acrodermatitis enteropathica, zinc-deficiency type (AEZ) Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. Gene ID: 55630 Database links: Entrez Gene: 55630 Human Entrez Gene: 72027 溶质载体家族蛋白39成员A4抗体Mouse Omim: 607059 Human SwissProt: Q6P5W5 Human SwissProt: Q78IQ7 Mouse Unigene: 521934 Human Unigene: 276829 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族蛋白39成员A4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid