溶质载体家族蛋白39成员A14抗体
规格:1mg/1ml
英文名: SLC39A14
别名: Cig19; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; S39AE_HUMAN; SLC39A14; Solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc tran
分子量: 51kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC39A14
交叉反应:Human, Chimpanzee,
细胞定位:细胞膜
溶质载体家族蛋白39成员A14抗体产品介绍:background: Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008] Function: May be able to transport iron (By similarity). Acts as a zinc-influx transporter. Subunit: Homotrimer. Subcellular Location: Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae. Tissue Specificity: Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland,溶质载体家族蛋白39成员A14抗体 left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes. Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. Gene ID: 23516 Database links: Entrez Gene: 464044 Chimpanzee Entrez Gene: 23516 Human Entrez Gene: 100387296 Marmoset (common) Entrez Gene: 213053 Mouse Entrez Gene: 100172692 Orangutan 溶质载体家族蛋白39成员A14抗体Omim: 608736 Human SwissProt: Q15043 Human SwissProt: Q75N73 Mouse SwissProt: Q5RAB7 Orangutan Unigene: 491232 Human Unigene: 270647 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:溶质载体家族蛋白39成员A14抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 发育生物学 信号转导 细胞分化
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid