溶质载体家族蛋白35成员D1抗体
规格：1mg/1ml
英文名： SLC35D1
别名： KIAA0260; MGC138236; S35D1_HUMAN; SLC35D1; Solute carrier family 35 (UDP GlcA/UDP GalNAc transporter), member D1; Solute carrier family 35 (UDP glucuronic acid/UDP N acetylgalactosamine dual transport
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC35D1
交叉反应：Human, Mouse, Rat, Pig, Cow, Guinea Pig, Cat,
细胞定位：细胞浆 细胞膜
产溶质载体家族蛋白35成员D1抗体品介绍：background: Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009] Function: Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in 溶质载体家族蛋白35成员D1抗体glucuronidation and/or chondroitin sulfate biosynthesis. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Ubiquitous. DISEASE: Defects in SLC35D1 are a cause of Schneckenbecken dysplasia (SCHBCKD) [MIM:269250]. Schneckenbecken dysplagia is a rare, autosomal recessive, lethal short-limbed skeletal dysplasia with platyspondylia. Similarity: Belongs to the TPT transporter family.溶质载体家族蛋白35成员D1抗体 SLC35D subfamily. Gene ID: 23169 Database links: Entrez Gene: 613734 Cow Entrez Gene: 23169 Human Entrez Gene: 242585 Mouse Entrez Gene: 733680 Pig Entrez Gene: 298280 Rat Omim: 610804 Human SwissProt: Q9NTN3 Human Unigene: 213642 Human Unigene: 281800 Mouse Unigene: 225024 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：溶质载体家族蛋白35成员D1抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid