溶质载体家族蛋白25成员38抗体
规格：1mg/1ml
英文名： SLC25A38
别名： FLJ20551; FLJ22703; S2538_HUMAN; slc25a38; Solute carrier family 25 member 38.
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC25A38
交叉反应：Human, Mouse, Cow, Rabbit, Sheep,
细胞定位：细胞膜
溶质载体家族蛋白25成员38抗体产品介绍：background: This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia.[provided by RefSeq, Mar 2010] Function: Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane. Subcellular Location: Mitochondrion inner membrane. Tissue Specificity: Preferentially expressed in erythroid cells. DISEASE: Defects in SLC25A38 are a cause of anemia sideroblastic pyridoxine-refractory autosomal recessive (PRARSA) 溶质载体家族蛋白25成员38抗体[MIM:205950]. A form of sideroblastic anemia not responsive to pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus. Similarity: Belongs to the mitochondrial carrier family. SLC25A38 subfamily. Contains 3 Solcar repeats. Gene ID: 54977 Database links: Entrez Gene: 512325 Cow 溶质载体家族蛋白25成员38抗体Entrez Gene: 477028 Dog Entrez Gene: 54977 Human Entrez Gene: 208638 Mouse Entrez Gene: 301067 Rat Entrez Gene: 100147784 Sheep Omim: 610819 Human SwissProt: Q5EAC0 Cow SwissProt: Q96DW6 Human SwissProt: Q91XD8 Mouse SwissProt: Q499U1 Rat SwissProt: S2538 Sheep Unigene: 369615 Human Unigene: 236656 Mouse Unigene: 21048 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产溶质载体家族蛋白25成员38抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid