溶质载体家族蛋白34成员A1抗体
规格:1mg/1ml
英文名: SLC34A1
别名: FRTS2; Na(+)-dependent phosphate cotransporter 2A; Na(+)/Pi cotransporter 2A; Na+-phosphate cotransporter type II; naPi-2a; NAPI-3; naPi2a; NAPI3; NPHLOP1; NPT2; NPTIIa; renal sodium-dependent phospha
分子量: 69kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC34A1
交叉反应:Human, Mouse, Rat, Pig, Rabbit, Sheep, Cat,
细胞定位:细胞膜
溶质载体家族蛋白34成员A1抗体产品介绍:background: This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] Function: May be involved in actively transporting phosphate into cells via Na+ cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. Subunit: Interacts via its C-terminal region with PDZK2 (By similarity). Interacts with SLC9A3R1. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Kidney and lung. 溶质载体家族蛋白34成员A1抗体DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:A disease characterized by decreased renal phosphate absorption, renal phosphate wasting, hypophosphatemia, hyperphosphaturia, hypercalciuria, nephrolithiasis and osteoporosis. Similarity: Belongs to the SLC34A transporter family. Gene ID: 6569 Database links: Entrez Gene: 282483 Cow Entrez Gene: 100735387 Guinea pig Entrez Gene: 100058397 Horse Entrez Gene: 6569 Human Entrez Gene: 20505 Mouse Entrez Gene: 100155735 Pig Entrez Gene: 733703 Pig Entrez Gene: 100009392 Rabbit Entrez Gene: 25548 Rat Entrez Gene: 443505 Sheep Omim: 182309 Human SwissProt: Q06495 溶质载体家族蛋白34成员A1抗体Human SwissProt: Q60825 Mouse SwissProt: Q28620 Rabbit SwissProt: Q06496 Rat SwissProt: O97704 Sheep Unigene: 936 Human Unigene: 276355 Mouse Unigene: 92022 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族蛋白34成员A1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid