溶质载体家族蛋白25成员A25抗体
规格:1mg/1ml
英文名: SLC25A25
别名: Calcium-binding mitochondrial carrier protein SCaMC-2; KIAA1896; MCSC; MGC105138; MGC119514; MGC119515; MGC119516; MGC119517; Mitochondrial ATP Mg/Pi carrier; Mitochondrial ATP-Mg/Pi carrier protein 3
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC25A25
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位:细胞膜
溶质载体家族蛋白25成员A25抗体产品介绍:background: The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012] Function: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides溶质载体家族蛋白25成员A25抗体, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. Subcellular Location: Mitochondrion inner membrane. Tissue Specificity: Present in various cell lines (at protein level). Widely expressed. Expressed in fetal and ***** liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus. Isoform 1 is present in all tissues tested. Isoform 2 expression is restricted to kidney and lung. Similarity: Belongs to the mitochondrial carrier family. Contains 3 EF-hand domains. Contains 3 Solcar repeats. Database 溶质载体家族蛋白25成员A25抗体links: Entrez Gene: 527786 Cow Entrez Gene: 114789 Human Entrez Gene: 227731 Mouse Entrez Gene: 246771 Rat Entrez Gene: 406541 Zebrafish Omim: 608745 Human SwissProt: Q0V7M4 Cow SwissProt: Q6KCM7 Human SwissProt: A2ASZ8 Mouse SwissProt: Q8K3P6 Rat SwissProt: A2CEQ0 Zebrafish Unigene: 5476 Human Unigene: 37395 Mouse Unigene: 473265 Mouse Unigene: 17644 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族蛋白25成员A25抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid