溶质载体家族蛋白22成员A2抗体
规格:1mg/1ml
英文名: SLC22A2
别名: MGC32628; OCT 2; OCT2; Organic cation transporter 2; Organic cation transporter; RP11-317M22.2; Solute carrier family 22 (organic cation transporter) member 2; Solute carrier family 22 member 2.
分子量: 63kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC22A2
交叉反应:Human,
溶质载体家族蛋白22成员A2抗体细胞定位:细胞膜
产品介绍:background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008] Function: SLC22A2 (solute carrier family 22 (organic cation transporter), member 2) is an organic cation transporter. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for 溶质载体家族蛋白22成员A2抗体elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is found primarily in the kidney, where it may mediate the first step in cation reabsorption. It plays important roles in the renal tubular secretion of cationic drugs. Subcellular Location: Plasma membrane Similarity: Belongs to the major facilitator (TC 2.A.1)superfamily. Organic溶质载体家族蛋白22成员A2抗体 cation transporter (TC 2.A.1.19) family. Gene ID: 6582 Database links: Entrez Gene: 6582 Human Entrez Gene: 20518 Mouse Entrez Gene: 29503 Rat Omim: 602608 Human SwissProt: O15244 Human SwissProt: O70577 Mouse SwissProt: Q9R0W2 Rat Unigene: 436385 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族蛋白22成员A2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid