溶质载体家族蛋白13成员A3抗体
规格:1mg/1ml
英文名: SLC13A3
别名: +dicarboxylate cotransporter 3; H sapiens mRNA for hepatocyte nuclear factor 4 gamma; hNaDC3; Na; Na(+)/dicarboxylate cotransporter 3; NaDC 3; NaDC-3; NADC3; S13A3_HUMAN; SDCT 2; SDCT2; SLC13A3; Sodiu
分子量: 67kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC13A3
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat,
细胞定位:细胞膜
溶质载体家族蛋白13成员A3抗体产品介绍:background: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008] Function: High-affinity sodium-dicarboxylate cotransporter that accepts 溶质载体家族蛋白13成员A3抗体a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate. Subcellular Location: Cell membrane. Tissue Specificity: Expression is highest in kidney. Detected in placenta, brain, liver and pancreas. Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily. Gene ID: 64849 Database links: Entrez Gene: 526291 Cow Entrez Gene: 485910 Dog Entrez Gene: 64849 Human Entrez Gene: 114644 Mouse Entrez Gene: 100738810 Pig Entrez Gene: 100355238 Rabbit Entrez Gene: 64846 Rat溶质载体家族蛋白13成员A3抗体 Omim: 606411 Human SwissProt: Q8WWT9 Human SwissProt: Q91Y63 Mouse SwissProt: Q9Z0Z5 Rat Unigene: 655498 Human Unigene: 250738 Mouse Unigene: 3587 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族蛋白13成员A3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid