DNA解旋酶Q1样抗体
规格：1mg/1ml
英文名： RECQ1
别名： ATP dependent DNA helicase Q1; DNA helicase Q1 like; DNA helicase RecQ like type 1; RECQ L1; RecQ protein like 1; RecQ protein like; RECQL; RECQL1.
分子量： 72kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RECQ1
交叉反应：Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
DNA解旋酶Q1样抗体产品介绍：background: The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' DNA解旋酶Q1样抗体and 3' UTRs, have been described. [provided by RefSeq, Jul 2008] Function: DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Subunit: Interacts with EXO1 and MLH1. Subcellular Location: Nuclear Tissue Specificity: High expression in heart, lung, skeletal muscle and kidney, low expression in brain. Similarity: Belongs to the helicase family. RecQ subfamily Contains 1 helicase DNA解旋酶Q1样抗体ATP-binding domain Contains 1 helicase C-terminal domain. Gene ID: 5965 Database links: Entrez Gene: 5965 Human Entrez Gene: 19691 Mouse Omim: 600537 Human SwissProt: P46063 Human SwissProt: Q9Z129 Mouse Unigene: 235069 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA解旋酶Q1样抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid