RNA结合蛋白35B抗体
规格：1mg/1ml
英文名： RBM35B/ESRP2
别名： Epithelial splicing regulatory protein 2; ESRP 2; ESRP2; ESRP2_HUMAN; FLJ21918; FLJ22248; RBM35B; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA binding protein 35B; RNA-binding mot
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBM35B/E
交叉反应：Human, Mouse, Rat, Cow, Rabbit,
细胞定位：细胞核
RNA结合蛋白35B抗体产品介绍：background: ESPR2 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009] Function: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. RNA结合蛋白35B抗体Subcellular Location: Nucleus. Tissue Specificity: Epithelial cell-specific. Similarity: Belongs to the ESRP family. Contains 3 RRM (RNA recognition motif) domains. Gene ID: 80004 Database links: Entrez Gene: 510878 Cow Entrez Gene: 80004 Human Entrez RNA结合蛋白35B抗体Gene: 77411 Mouse Entrez Gene: 307810 Rat Omim: 612960 Human SwissProt: Q9H6T0 Human SwissProt: Q8K0G8 Mouse SwissProt: B2RYJ8 Rat Unigene: 436585 Human Unigene: 592053 Human Unigene: 183003 Mouse Unigene: 137974 Rat Unigene: 231924 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA结合蛋白35B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid