RNA结合蛋白35A抗体
规格：1mg/1ml
英文名： RBM35A/ESRP1
别名： Epithelial splicing regulatory protein 1; Esrp1; ESRP1_HUMAN; FLJ20171; RBM35A; RMB35A; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A.
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBM35A
交叉反应：Human, Mouse, Rat, Dog, Pig, Rabbit,
细胞定位：细胞核
RNA结合蛋白35A抗体产品介绍：background: ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009] Function: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.RNA结合蛋白35A抗体 Subcellular Location: Nucleus. Tissue Specificity: Epithelial cell-specific. Similarity: Belongs to the ESRP family. Contains 3 RRM (RNA recognition motif) domains. Gene ID: 54845 Database links: Entrez Gene: 538640 Cow Entrez Gene: 487054 Dog Entrez Gene: RNA结合蛋白35A抗体100055214 Horse Entrez Gene: 54845 Human Entrez Gene: 207920 Mouse Entrez Gene: 100156237 Pig Entrez Gene: 500409 Rat Omim: 612959 Human SwissProt: Q6NXG1 Human SwissProt: Q3US41 Mouse SwissProt: B2RYD2 Rat Unigene: 487471 Human Unigene: 387719 Mouse Unigene: 161971 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA结合蛋白35A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid