锌指蛋白384抗体
规格：1mg/1ml
英文名： ZNF384
别名： CAG repeat protein 1; CAGH1A; CAS interacting zinc finger protein; CAS-interacting zinc finger protein; CIZ; ERDA2; GH1A; NMP4; NP; Nuclear matrix protein 4; Nuclear matrix transcription factor 4; TNR
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF384
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
锌指蛋白384抗体细胞定位：细胞核
产品介绍：background: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A 锌指蛋白384抗体related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011] Function: Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 8 C2H2-type zinc fingers. Gene ID: 171017 Database links: Entrez Gene: 515007 Cow Entrez Gene: 486723 Dog Entrez Gene: 100726713 Guinea pig Entrez Gene: 100059879 Horse Entrez Gene: 171017 Human锌指蛋白384抗体 Entrez Gene: 269800 Mouse Entrez Gene: 100516975 Pig Entrez Gene: 100341607 Rabbit Entrez Gene: 171018 Rat Omim: 609951 Human SwissProt: Q8TF68 Human SwissProt: Q9EQJ4 Rat Unigene: 103315 Human Unigene: 708126 Human Unigene: 714839 Human Unigene: 9637 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白384抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 转录调节因子 锌指蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid