RNA结合蛋白17抗体
规格：1mg/1ml
英文名： RBM17
别名： 45 kDa-splicing factor; RBM 17; Rbm17; RNA binding motif protein 17; RNA binding motif protein17; RNA-binding motif protein 17; SPF 45; SPF45; SPF45_HUMAN; Splicing factor (45 kD); Splicing factor (45
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBM17
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞核
RNA结合蛋白17抗体产品介绍：background: This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009] Function: Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting RNA结合蛋白17抗体frameshift leads to sickle cell anemia. Subcellular Location: Nucleus. Similarity: Contains 1 G-patch domain. Contains 1 RRM (RNA recognition motif) domain. Gene ID: 84991 Database links: Entrez Gene: 84991 Human Entrez Gene: 76938 Mouse RNA结合蛋白17抗体Entrez Gene: 291295 Rat Omim: 606935 Human SwissProt: Q96I25 Human SwissProt: Q8JZX4 Mouse Unigene: 498548 Human Unigene: 182769 Mouse Unigene: 20694 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA结合蛋白17抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid