SH3结构域结合蛋白5抗体
规格:1mg/1ml
英文名: SH3BP5
别名: 3BP5_HUMAN; OTTHUMP00000208289; OTTHUMP00000208291; OTTHUMP00000208294; SAB; SH3 binding protein; SH3 domain binding protein 5 (BTK associated); SH3 domain binding protein 5; SH3 domain binding protei
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SH3BP5
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
SH3结构域结合蛋白5抗体产品介绍:background: Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate. Similarity: Belongs to the SH3BP5 family. Gene ID: 9467 Database links: Entrez Gene: 9467 Human Entrez Gene: 520254 Cow Entrez Gene: 80851 Human Entrez Gene: 24056 Mouse Entrez Gene: 79566 Mouse Entrez Gene:SH3结构域结合蛋白5抗体 117186 Rat Omim: 605612 Human SwissProt: Q0V8K7 Cow SwissProt: O60239 Human SwissProt: Q7L8J4 Human SwissProt: Q99LH9 Mouse SwissProt: Q9Z131 Mouse SwissProt: Q91Y80 Rat Unigene: 11005 Cow Unigene: 257761 Human Unigene: 726063 SH3结构域结合蛋白5抗体Human Unigene: 290534 Mouse Unigene: 383198 Mouse Unigene: 163321 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SH3结构域结合蛋白5抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞凋亡 激酶和磷酸酶 **细胞 b-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid