脑瘤相关基因抗体
规格:1mg/1ml
英文名: Netrin G2 Ligand
别名: BAG; Brain tumor associated protein LRRC4; Brain tumor-associated protein BAG; Leucine rich repeat containing 4; Leucine rich repeat containing protein 4; Leucine-rich repeat-containing protein 4; Lrr
分子量: 68kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LRRC4
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位:细胞膜
脑瘤相关基因抗体产品介绍:background: This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitement of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma. Function: Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). Subunit: Interacts with NTNG2 (By similarity). Interacts 脑瘤相关基因抗体with DLG4 (By similarity). Forms a complex with DLG4 and with NMDA receptors. Subcellular Location: Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Tissue Specificity: Specifically expressed in brain. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Contains 9 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Gene ID: 64101 脑瘤相关基因抗体Database links: Entrez Gene: 64101 Human Entrez Gene: 192198 Mouse Entrez Gene: 641521 Rat Omim: 610486 Human SwissProt: Q9HBW1 Human SwissProt: Q99PH1 Mouse SwissProt: Q45R42 Rat Unigene: 655003 Human Unigene: 443660 Mouse Unigene: 198672 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑瘤相关基因抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid