胞吞蛋白Endophilin 2抗体
规格：1mg/1ml
英文名： Endophilin II
别名： SH3 containing Grb 2 like 1 protein; Endophilin II; CNSA1; EEN; EEN fusion partner of MLL; Endophilin-2; Endophilin-A2; Extra 11 19 leukemia fusion gene; Extra eleven-nineteen leukemia fusion gene pro
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Endophil
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
胞吞蛋白Endophilin 2抗体细胞定位：细胞浆
产品介绍：background: This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature. Subcellular Location: Cytoplasm. Early endosome membrane. Associated with postsynaptic endosomes in hippocampal neurons. 胞吞蛋白Endophilin 2抗体Tissue Specificity: Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus. DISEASE: Note=In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene. Similarity: Belongs to the endophilin family. Contains 1 BAR domain. Contains 1 SH3 domain. Gene ID: 6455 Database links: Entrez Gene: 512719 Cow Entrez Gene: 6455 Human Entrez Gene: 20405 Mouse Entrez Gene: 81922 Rat Omim: 601768 Human SwissProt: Q2KJA1 Cow SwissProt: Q99961 Human SwissProt: Q62419 Mouse SwissProt: 胞吞蛋白Endophilin 2抗体O35964 Rat Unigene: 97616 Human Unigene: 1773 Mouse Unigene: 8762 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胞吞蛋白Endophilin 2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid