磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体
规格：1mg/1ml
英文名： phospho-RASGRP3 (Thr133)
别名： RASGRP3 (phospho T133); p-RASGRP3 (phospho T133); Calcium and DAG-regulated guanine nucleotide exchange factor III; Grp3; GRP3_HUMAN; Guanine nucleotide exchange factor for Rap1; Kiaa0846; RAS guanyl
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞膜
磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体产品介绍：background: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体[PubMed 10934204]).[supplied by OMIM, Mar 2008] Function: Guanine nucleotide exchange factor (GEF) for Ras and Rap1. Similarity: Belongs to the RASGRP family. Contains 2 EF-hand domains. Contains 1 N-terminal Ras-GEF domain. Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Ras-GEF domain. Gene ID: 25780 Database links: Entrez Gene: 25780 Human Entrez Gene: 磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体240168 Mouse Omim: 609531 Human SwissProt: Q8IV61 Human Unigene: 143674 Human Unigene: 329203 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid