Ras相关蛋白RAB-12抗体
规格:1mg/1ml
英文名: RAB12
别名: Putative Ras related protein Rab 12; RAB12; RAB12, member RAS oncogene family; RAB12_HUMAN; Ras-related protein Rab-12.
分子量: 27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RAB12
交叉反应:Human, Rat,
细胞定位:
Ras相关蛋白RAB-12抗体产品介绍:Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation,Ras相关蛋白RAB-12抗体 movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity). Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the small GTPase superfamily. Rab family. Gene ID: 201475 Database links: Entrez Gene: 201475 Human SwissProt: Ras相关蛋白RAB-12抗体Q6IQ22 Human Unigene: 270074 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产Ras相关蛋白RAB-12抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid