PXK蛋白抗体
规格：1mg/1ml
英文名： PXK
别名： FLJ20335; K-ATPase; Modulator of Na.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PXK
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
PXK蛋白抗体产品介绍：background: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Function: Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. Subcellular Location: Cytoplasm. Cell membrane. Also associates with tPXK蛋白抗体he plasma membrane. Isoform 3 is present throughout the cell. Tissue Specificity: Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated. Similarity: Belongs to the protein kinase superfamily. Contains 1 protein kinase domain. Contains 1 PX (phox homology) domain. Contains 1 WH2 domain. Gene ID: 54899 Database links: Entrez Gene: 614093 Cow Entrez Gene: 54899 Human Entrez Gene: 218699 Mouse Entrez Gene: 306203 Rat Omim: PXK蛋白抗体611450 Human SwissProt: Q7Z7A4 Human SwissProt: Q8BX57 Mouse SwissProt: Q4FZZ1 Rat Unigene: 190544 Human Unigene: 29515 Mouse Unigene: 86175 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PXK蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid