富含嘌呤元件结合蛋白A抗体
规格：1mg/1ml
英文名： PURA
别名： PUR ALPHA; PUR1; purA; PURA_HUMAN; PURALPHA; Purine rich element binding protein A; Purine rich single stranded DNA binding protein alpha; Purine-rich single-stranded DNA-binding protein alpha; Transc
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PURA
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig, Cat, Danio rerio
细胞定位：细胞核
富含嘌呤元件结合蛋白A抗体产品介绍：background: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq,富含嘌呤元件结合蛋白A抗体 Jul 2008] Function: This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination. Subcellular Location: Nucleus. Similarity: Belongs to the PUR DNA-binding protein family. Gene ID: 5813 Database links: Entrez Gene: 5813 Human Entrez Gene: 19290 Mouse富含嘌呤元件结合蛋白A抗体 Entrez Gene: 307498 Rat Omim: 600473 Human SwissProt: Q00577 Human SwissProt: P42669 Mouse SwissProt: P86252 Rat Unigene: 443121 Human Unigene: 231802 Mouse Unigene: 482241 Mouse Unigene: 41055 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产富含嘌呤元件结合蛋白A抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid