磷酸化胸苷激酶1抗体
规格:1mg/1ml
英文名: phospho-Thymidine Kinase 1 (Ser13)
别名: Thymidine Kinase 1 (phospho S13); p-Thymidine Kinase 1 (phospho S13); cytosolic; KITH_HUMAN; Thymidine kinase 1; Thymidine kinase 1 soluble; Thymidine kinase 1 soluble isoform; Thymidine kinase; Thymi
分子量: 25kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthesised phosphopeptide derived from human
交叉反应:Human, Dog, Pig, Hamster,
细胞定位:细胞浆
磷酸化胸苷激酶1抗体产品介绍:background: Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in磷酸化胸苷激酶1抗体 the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer. Subcellular Location: Cytoplasm. Post-translational modifications: Phosphorylated on Ser-13 in mitosis. Similarity: Belongs to the thymidine kinase family. Gene ID: 7083 Database links: Entrez Gene: 7083 Human Entrez Gene: 21877 Mouse Entrez磷酸化胸苷激酶1抗体 Gene: 24834 Rat Omim: 188300 Human SwissProt: P04183 Human SwissProt: P04184 Mouse SwissProt: P27158 Rat Unigene: 515122 Human Unigene: 2661 Mouse Unigene: 195325 Rat Unigene: 216486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:磷酸化胸苷激酶1抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid