Opticin蛋白抗体
规格:1mg/1ml
英文名: Opticin
别名: Oculoglycan; OPT; OPT_HUMAN; OPTC; Opticin.
分子量: 37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Opticin
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位:分泌型蛋白
Opticin蛋白抗体产品介绍:background: Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided byOpticin蛋白抗体 RefSeq, Jul 2008] Function: Binds collagen fibrils. Subcellular Location: Secreted > extracellular space > extracellular matrix.Entrez Gene: 26254 Human Entrez Gene: 269120 Mouse Entrez Gene: 304802 Rat Omim: 605127 Human SwissProt: Q9UBM4 Human SwissProt: Q920A0 Mouse Unigene: 632468 Human Unigene: 59985 Mouse Tissue Specificity: Retina, iris, ligament, skin and fetal liver. Post-translational modifications: O-glycosylated. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. Contains 6 LRR (leucine-rich) repeats. Opticin蛋白抗体Contains 1 LRRNT domain. Gene ID: Database links: Entrez Gene: 26254 Human Entrez Gene: 269120 Mouse Entrez Gene: 304802 Rat Omim: 605127 Human SwissProt: Q9UBM4 Human SwissProt: Q920A0 Mouse Unigene: 632468 Human Unigene: 59985 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:Opticin蛋白抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid