硒蛋白SEP15抗体
规格：1mg/1ml
英文名： 42628
别名： 15 kDa selenoprotein; Sep15; SEP15_HUMAN.
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SEP15
交叉反应：Human, Mouse, Rat, Pig, Cow, Zebrafish, Sheep,
细胞定位：
硒蛋白SEP15抗体产品介绍：background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum. 硒蛋白SEP15抗体Subcellular Location: Endoplasmic reticulum lumen. The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum. Tissue Specificity: Higher levels in prostate and thyroid gland. Similarity: Belongs to the selenoprotein M/SEP15 family. Gene ID: 9403 Database links: Entrez Gene: 614360 Cow Entrez Gene: 9403 Human Entrez Gene: 93684 Mouse Entrez Gene: 100038009 Pig Entrez Gene: 113922 Rat硒蛋白SEP15抗体 Entrez Gene: 352923 Zebrafish Omim: 606254 Human SwissProt: A8YXY3 Cow SwissProt: O60613 Human SwissProt: Q9ERR7 Mouse SwissProt: A1Z623 Pig SwissProt: Q923V8 Rat SwissProt: Q802F3 Zebrafish Unigene: 362728 Human Unigene: 29812 Mouse Unigene: 1124 Rat Unigene: 11333 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硒蛋白SEP15抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid