泛素样蛋白特异性蛋白酶2抗体
规格：1mg/1ml
英文名： SENP2
别名： Axam2; DKFZp762A2316; KIAA1331; Senp2; SERP2; SENP2_HUMAN; Sentrin specific protease 2; Sentrin-specific protease 2; Sentrin/SUMO specific protease SENP2; Sentrin/SUMO-specific protease SENP2; SMT3 sp
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SENP2
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
泛素样蛋白特异性蛋白酶2抗体产品介绍：background: SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004] Function: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Subcellular Location: Nucleus >泛素样蛋白特异性蛋白酶2抗体 nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm and nucleus. Post-translational modifications: Polyubiquitinated; which leads to proteasomal degradation. Similarity: Belongs to the peptidase C48 family. Gene ID: 59343 Database links: Entrez Gene: 59343 Human Entrez Gene: 75826 Mouse Entrez Gene: 78973 Rat Omim: 608261 Human SwissProt: Q9HC62 Human SwissProt: 泛素样蛋白特异性蛋白酶2抗体Q91ZX6 Mouse SwissProt: Q9EQE1 Rat Unigene: 401388 Human Unigene: 297431 Mouse Unigene: 9367 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
泛素样蛋白特异性蛋白酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid