硒蛋白M抗体
规格:1mg/1ml
英文名: Selenoprotein M
别名: Selenoprotein-M; Selenoprotein SelM; SELM; SELM_HUMAN; SelM protein; SEPM.
分子量: 14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Selenopr
交叉反应:Human,
细胞定位:细胞浆
硒蛋白M抗体产品介绍:background: Selenoprotein M is widely expressed and expressed highly in the mammalian brain. It is localized to the perinuclear structures (Golgi/ER). A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. The roles of Selenoprotein M have not been clearly identified until present time. Function: May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. Subcellular Location: Cytoplasm; perinuclear region. Endoplasmic reticulum Probable.硒蛋白M抗体 Golgi apparatus Probable. Note: Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum. Similarity: Belongs to the selenoprotein M/SEP15 family. Gene ID: 140606 Database links: Entrez Gene: 140606 Human Entrez Gene: 114679 Mouse硒蛋白M抗体 Entrez Gene: 498398 Rat Omim: 610918 Human SwissProt: Q8WWX9 Human SwissProt: Q8VHC3 Mouse Unigene: 55940 Human Unigene: 34046 Mouse Unigene: 8166 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硒蛋白M抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 **学 发育生物学 神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid