白介素2受体β链/IL-2Rβ 抗体
规格：1mg/1ml
英文名： IL2 Receptor beta
别名： Imterleukm-2 Receptor beta; CD 122; CD122; CD122 antigen; High affinity IL 2 receptor beta subunit; High affinity IL 2 receptor subunit beta; High affinity IL2 receptor beta subunit; High affinity IL2
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD122
交叉反应：Human, Mouse, Rat, Cow, Horse,
细胞定位：细胞膜
白介素2受体β链/IL-2Rβ 抗体产品介绍：background: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]. Function: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Subunit: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high 白介素2受体β链/IL-2Rβ 抗体affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the type I cytokine receptor family. 白介素2受体β链/IL-2Rβ 抗体Type 4 subfamily. Contains 1 fibronectin type-III domain. Gene ID: 3560 Database links: Entrez Gene: 3560 Human Entrez Gene: 16185 Mouse Omim: 146710 Human SwissProt: P14784 Human SwissProt: P16297 Mouse Unigene: 474787 Human Unigene: 35287 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：白介素2受体β链/IL-2Rβ 抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 细胞粘附分子 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid