钠离子/牛磺胆酸共转运蛋白抗体
规格：1mg/1ml
英文名： SLC10A1
别名： Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholat
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NTCP
交叉反应：Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位：细胞膜
钠离子/牛磺胆酸共转运蛋白抗体产品介绍：background: Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM] Function: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.钠离子/牛磺胆酸共转运蛋白抗体 Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Liver and kidney Similarity: Belongs to the sodium:bile acid symporter family. Gene ID: 6554 Database links: Entrez Gene: 6554 Human Entrez Gene: 20493 Mouse Entrez Gene: 24777 Rat Omim: 182396 Human SwissProt: Q14973 Human SwissProt: O08705 Mouse SwissProt: P26435 Rat Unigene: 952 Human Unigene:钠离子/牛磺胆酸共转运蛋白抗体 341781 Mouse Unigene: 9913 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NTCP（钠离子/牛磺胆酸共转运蛋白）(钠离子-牛磺胆酸共转运多肽)Na+/taurocholate Cotransporting Polypeptide是 肝脏的胆汁酸盐吸收主要是钠离子依赖性转运子NTCP介导的，主要吸收牛磺胆酸，是肝细胞特有的一种转运载体，分布在肝细胞基侧膜在肝小叶和肝的腺泡表达较多。 有学者认为：NTCP是乙肝病毒的细胞钠离子/牛磺胆酸共转运蛋白抗体表面受体分子，是HBV和HDV的功能受体，这些研究将有待于科研人员的进一步证实。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 信号转导 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid