肝癌易感蛋白3抗体
规格:1mg/1ml
英文名: PSMG2/HCCA3
别名: CD40 ligand activated specific transcript 3; CLAST3; HCCA3; Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-susceptibility protein 3; HSPC260; HsT1707; Likely ortholog of mou
分子量: 29kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PSMG2/HC
交叉反应:Human, Cow,
细胞定位:细胞核
肝癌易感蛋白3抗体产品介绍:Function: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue. Post-translational 肝癌易感蛋白3抗体modifications: Degraded by the proteasome upon completion of 20S proteasome maturation. Similarity: Belongs to the PSMG2 family. Gene ID: 56964 Database links: Entrez Gene: 56984 Human Entrez Gene: 533993 Cow Entrez Gene: 107047 Mouse Entrez 肝癌易感蛋白3抗体Gene: 291539 Rat Omim: 609702 Human SwissProt: Q2NL24 Cow SwissProt: Q969U7 Human SwissProt: Q9EST4 Mouse Unigene: 464652 Human Unigene: 150701 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肝癌易感蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid