蛋白酶体组装分子伴侣1抗体
规格：1mg/1ml
英文名： PSMG1
别名： AW552102; c21 LRP; PSMG1_HUMAN; C21LRP; Chromosome 21 leucine rich protein; Down syndrome critical region gene 2; Down syndrome critical region protein 2; Down syndrome critical region protein 2 homol
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PSMG1
交叉反应：Human,
细胞定位：细胞浆
蛋白酶体组装分子伴侣1抗体产品介绍：background: PSMG1 is a chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. There are two named isoforms. Function: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Subunit: Forms a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer interacts directly with the蛋白酶体组装分子伴侣1抗体 PSMA5 and PSMA7 proteasome alpha subunits. Subcellular Location: Cytoplasm. Endoplasmic reticulum. Tissue Specificity: In the *****, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines. Post-translational modifications: Degraded by the proteasome upon completion of 20S proteasome maturation. Similarity: Belongs to the PSMG1蛋白酶体组装分子伴侣1抗体 family. Gene ID: 8624 Database links: Entrez Gene: 8624 Human Entrez Gene: 56088 Mouse Entrez Gene: 288236 Rat Omim: 605296 Human SwissProt: O95456 Human SwissProt: Q9JK23 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酶体组装分子伴侣1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid