核运输因子1抗体
规格：1mg/1ml
英文名： NXT1
别名： MTR2; MTR2, yeast, homolog of; NTF2 like export factor 1; NTF2 related export protein 1; NTF2-related export protein 1; NUTF like export factor 1; NXT1; NXT1_HUMAN; P15; Protein P15.
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NXT1
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞核 细胞浆
核运输因子1抗体产品介绍：background: The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] Function: Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, 核运输因子1抗体and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5. Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. Similarity: Contains 1 NTF2 domain. Gene ID: 29107 Database links: Entrez Gene: 29107 Human Entrez Gene: 520351 Cow Entrez Gene: 56488 Mouse Entrez Gene: 296219 Rat Omim: 605811 Human SwissProt:核运输因子1抗体 Q2KIW0 Cow SwissProt: Q9UKK6 Human SwissProt: Q9QZV9 Mouse Unigene: 516933 Human Unigene: 34663 Mouse Unigene: 8541 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核运输因子1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：染色质和核信号 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid